Annotation of mouse endothelia

The skin, or integument, consists of two major layers: the epidermis, composed of stratified squamous epithelium that is keratinized, and the dermis, composed of connective tissue.

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VE-cadherin proteins label the endothelial cell junctions of the capillaries in the dermis of the skin from a mouse embryo at E15.5. Ep, epidermis; De, dermis.

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High-magnification view of the endothelium in the dermis.

The kidney is an epithelial tissue composed of the uriniferous tubules. The uriniferous tubules consists in several segments, e.g., the proximal tubule, the loop of Henle, the distal tubule and the collecting duct.

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VE-cadherin proteins label the endothelial cell junctions of the capillaries in the stroma of the kidney from a mouse embryo at E15.5.

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High-magnification view of the endothelium in the kidney.

The lung is made of a type of epithelial structure known as alveolus. The alveolus is lined with the alveolar cells, extremely thin squamous epithelial cells. Groups of alveoli cluster into alveolar sacs.

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VE-cadherin proteins label the endothelial cell junctions of the capillaries in the lung from a mouse embryo at E15.5.

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High-magnification view of the endothelium in the lung.

The gut is lined with simple columnar epithelium, which serves two main functions: absorbing nutrients and restricting the entry of harmful substances. As part of its protective role, the gut epithelium forms a mucosal barrier.

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VE-cadherin proteins label the endothelial cell junctions of the capillaries in the gut from a mouse embryo at E15.5. Muc, mucosa; SubM, submucosa.

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High-magnification view of the intestinal endothelium in the submucosa.

The liver is a glandular tissue made of a series of ducts of increasing diameter and complexity, beginning with the bile canaliculi between individual hepatocytes and ending with the common bile duct.

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VE-cadherin proteins label the endothelial cell junctions of the capillaries in the liver from a mouse embryo at E15.5. p.v., portal vein.

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High-magnification view of the endothelium in the liver.

The eye is a complex sensory organ. The wall of the eye consists of three concentric layers: the retina, the inner neural layer; the uvea, the middle vascular layer; and the corneosclera, the outer epithelial layer.

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VE-cadherin proteins label the endothelial cell junctions of the capillaries in the retina of the eye from a mouse embryo at E15.5.

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High-magnification view of the endothelium in the retina.

The brain is a neural tissue. The blood-brain barrier is a semipermeable pathway made of the endothelial cell that allows solutes in the circulating blood to selectively cross into the brain.

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VE-cadherin proteins label the endothelial cell junctions of the capillaries in the cerebral cortex of the brain from a mouse embryo at E15.5.

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High-magnification view of the endothelium in the brain.

The skeletal muscle is a type of striated muscle. The skeletal muscle cells, often known as muscle fibers, are a multinucleated syncytium formed by the fusion of individual muscle cells, the myoblasts.

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VE-cadherin proteins label the endothelial cell junctions of the capillaries in the intercostal muscle from a mouse embryo at E15.5.

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High-magnification view of the endothelium in the intercostal muscle.

The artery is a blood vessel that takes oxygenated blood away from the heart to one or more tissues of the body (liver, lungs, brain etc.).

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VE-cadherin proteins label the endothelial cell junctions of the artery and the arteriole from a mouse embryo at E15.5.

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High-magnification view of the endothelium in the artery.