Anti-AGTR2 (AT2) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

Angiotensin-II receptors (type 1 and type 2) are a class of G protein-coupled receptors with angiotensin-II as their ligands. They play a role of signal transduction in the renin-angiotensin system to mediate the effect of vasoconstriction of angiotensin-II.

The type 2 of angiotensin-II receptor, also known as AT2 or AGTR2, is encoded by the AGTR2 gene in human. The AGTR2 protein contains seven transmembrane domains and multiple extracellular and intracellular domains.

AGTR2 is mainly expressed by fetal tissues and considered to play a neuronal role.