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ATP2A1 (SERCA1) antibody labeling of embryonic mouse liver

ATP2A1 (SERCA1) antibody labeling of embryonic mouse liver

ATP2A1 proteins are found in the endoplasmic reticulum of the hepatocytes in the liver from a mouse embryo at E12.5.

ATP2A1 (SERCA1) antibody

$155.00 – $435.00

Item Cat No.: 54031

Antibody: Rat ATP2A1 (SERCA1) Polyclonal Antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, mouse, rat

Anti-ATP2A1 (SERCA1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

Optional Blocking Peptide

FFPE Specific Antibody

FFPE-specific recognition antibodies are made against the same epitope sequence with novel cross-linking and stabilizing technique to lock the conformational state of epitope in a folded state similar to aldehyde induced fixation.

Western Blot Specific Antibody

Western blot-specific recognition antibodies are made against the same epitope sequence with novel denaturing and stabilizing technique to prevent the natural folding of epitope in order to lock its conformation in unfolded state.

Product price: $155.00
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Anti-ATP2A1 (SERCA1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (SERCA1) is an enzyme that is encoded by the ATP2A1 gene in human. ATP2A1 catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the endoplasmic reticulum lumen. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise.

Host/Isotype: Rat/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (14-aa) derived from the N-terminal cytoplasmic region of human ATP2A1 protein

Species homology of immunogen: Synthetic peptide sequence is identical to mouse or rat sequence

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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Julie Craft Van De Weghe, PhD

School of Medicine | University of Washington

"The assay is a homophilic interaction mediated cell adhesion on purified protein (in this case, immobilized purified Pcdhga9 to Pcdhga9 expressed on cell surface). Compared to control, cell adhesion is reduced in the presence of Pcdhga9 monoclonal antibody supernatants!"

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