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ATP6V1B1 (ATP6B1) antibody

$99.00$295.00

Item Cat No.: 20901

Antibody: Rat ATP6V1B1 (ATP6B1) Polyclonal Antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, mouse, rat

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Anti-ATP6V1B1 (ATP6B1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

V-type proton ATPase V1 domain subunit B1, kidney isoform, is an enzyme that is encoded by the ATP6V1B1 gene in human. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site.

Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness (DRTA2) (OMIM #267300).

This antibody can be used with anti-Aqp2 or anti-Pendrin to differentiate the cell types in kidney collecting ducts.

Host/Isotype: Rat/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (14-aa) derived from the C-terminal region of mouse ATP6V1B1 protein

Species homology of immunogen: Synthetic peptide sequence is identical to rat sequence (showing 71.4% homology to human sequence)

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C


For Research Use Only. Not for use in clinical diagnostics.

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