Anti-CACNA1H (Cav3.2) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Calcium voltage-gated channel subunit alpha 1H, also known as Cav3.2, is a T-type voltage-dependent calcium channel that is encoded by the CACNA1H gene in human. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. Variants of Cav3.2 with increased channel activity contribute to susceptibility to idiopathic generalized epilepsy (IGE).
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