Anti-Cadherin-16 (Cdh16) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Cadherin-16 is a protein that is encoded by the Cdh16 gene in human. Cadherin-16 is also known as kidney specific cadherin (Ksp-cadherin). Cadherin-16 belongs to the classic cadherin protein superfamily.
The cadherin protein features an amino-terminal extracellular domain or ectodomain or EC domain that is followed by a transmembrane domain and a carboxyl-terminal intracellular domain. The cadherin ectodomain plays an adhesive role whereas the intracellular domain mediates cadherin-catenin interactions.
Cadherin-16 is exclusively expressed in the kidney, where it plays a vital role in kidney development.
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