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CASPR1 (CNTNAP1 or Paranodin) antibody


Item Cat No.: 02101

Antibody: Rat Anti-CASPR1 (CNTNAP1 or Paranodin) polyclonal antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, Mouse, Rat


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Anti-CASPR1 (CNTNAP1 or Paranodin) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

CASPR1 also known as Contactin associated protein 1 (CNTNAP1), or Paranodin or Neurexin IV, is a protein that is encoded by the CNTNAP1 gene in human. CASPR1 is a member of the neurexin family of proteins. CASPR1 consists in a large extracellular domain with multiple Laminin G-like 1 motifs, a transmembrane domain and a cytoplasmic tail. CASPR1 is a membrane protein found in the neuronal cell membrane in the paranodal section of the axon in myelinated nerves, between the Nodes of Ranvier, which contains Na+ channels, and the juxtaparanode, which contains K+ channels.

Host/Isotype: Rat/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (16-aa) derived from the C-terminal region of human CASPR1 protein

Species homology of immunogen: Synthetic peptide sequence is identical to mouse or rat sequence

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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