Anti-CCR4 (CD194) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.
Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. C-C chemokine receptor type 4 (CCR4) is a member of the G protein-coupled receptors, which is encoded by the CCR4 gene in human. CCR4 is highly expressed on leukemic cells in cutaneous T-cell lymphoma (CTCL).
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