CEP112 (CCDC46) antibody labeling of mouse retina
CEP112 proteins are found in the basal bodies/centrioles (arrow) of the connecting cilia in the photoreceptor cells as well as in the centrioles of the muller cells (arrow heads) and in the centrioles of bipolar cells in the INL of the mouse retina. IS: inner segment; ONL: outer nuclear layer; OPL: outer plexiform layer; INL: inner nuclear layer; IPL: inner plexiform layer.
CEP112 in the developing lung
CEP112 proteins are localized to the centrosomes of the alveolar epithelium as well as to the motile cilia of the epithelium lining the bronchiole (b.) in the lung from a mouse embryo at E15.5.
CEP112 in the developing kidney
CEP112 proteins are localized to the centrosomes in the primordial kidney epithelium including the tubular epithelium (t.) from a mouse embryo at E15.5.
CEP112 in the developing muscle
CEP112 proteins are localized to the centrosomes of the intercostal muscle cells in a mouse embryo at E15.5.
$155.00 – $435.00
Anti-CEP112 (CCDC46) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Anti-CEP112 (CCDC46) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Centrosomal protein of 112 kDa (CEP112), also known as CCDC46, is encoded by the CEP112 gene in human. CEP112 is a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. It is also a component of the centrosome in mammalian cells.
Host/Isotype: Rabbit/IgG
Class: Polyclonal
Immunogen: Synthetic peptide (15-aa) derived from the C-terminal region of mouse CEP112 protein
Species homology of immunogen: Synthetic peptide sequence is identical to rat sequence (showing 93.3% homology to human sequence)
Conjugation: Unconjugated
Purification: Affinity chromatography
Storage buffer: PBS, pH 7.2, 0.1% sodium azide
Storage condition: –20°C
For Research Use Only. Not for use in clinical diagnostics.
Materials and reagents Expand Equipment Leica CM1950 automatic sectioning cryostat. Thermo Fisher Scientific round (12 mm diameter) cover glass (thickness No 1.5). Thermo Fisher Scientific ColorFrostTM Plus slides made of positively charge uncoated glass. Tissue-tek Expand Tissue-tek OCT 4583 compound from VWR. Tissue-tek cryomolds from VWR. Blocking buffer Expand BLOCK Solution NaCl 8 g […]
Materials and reagents Expand Leica CM1950 automatic sectioning cryostat. Thermo Fisher Scientific round (12 mm diameter) cover glass (thickness No 1.5). Thermo Fisher Scientific ColorFrostTM Plus slides made of positively charge uncoated glass. Tissue-tek Expand Tissue-tek OCT 4583 compound from VWR. Tissue-tek cryomolds from VWR. Buffers Expand 0.5% paraformaldehyde in PBS NaCl 8 g […]
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