Anti-Connexin-26 (Cx26 or Gjb2) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

Connexins are the structural proteins making the gap junction. Each gap junction is composed of two hemichannels, or connexons, which consist of a hexameric assembly of connexin proteins.

Connexin-26 is encoded by the  Gjb2 gene in human. Connexin-26 is also known as gap junction protein beta 2. Connexins have four transmembrane domains, two extracellular loops, amino- and carboxyl-terminal cytoplasmic domains, and a cytoplasmic turn motif.

Mutations in Gjb2 cause a recessive form of congenital deafness DFNB1 (OMIM 220290), also known as connexin-26 deafness or Gjb2-related deafness.