Anti-GRIN2A (GluN2A) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Glutamate ionotropic receptor NMDA type subunit 2a (GRIN2A), also known as GluN2A, is encoded by the GRIN2A gene in human. GRIN2A is a subunit of N-methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily. NMDA receptors function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. NMDA receptors play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Mutations in the GRIN2A gene are associated with focal epilepsy and speech disorder with or without cognitive disability.
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