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Histopathology Service

$49.00$119.00

Histopathology Service provides standard and customized research-specific histology and pathology services including routine and special histological stains as well as immunofluorescence and immunohistochemistry with BiCell Scientific antibodies and in situ hybridization against mRNA or microRNA.

Optional Digital Imaging Add-on

Product price: $49.00
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Histopathology Service provides standard and customized research-specific histology and pathology services including routine formalin fixation, and paraffin embedding and sectioning, and cryosectioning of frozen sections.

Histopathology Service offers routine and special histological stains, immunohistochemistry and immunofluorescence, and in situ hybridization against mRNA or microRNA, as well as digitized imaging data collection using Nikon Ni-E motorized microscope equipped with CCD fluorescence camera and bright-field color camera.

Histopathology Service has worked with a wide variety of tissues and staining techniques from mice, rats, non-human primates, pigs and humans and can develop protocols for new antibodies.

  • Tissue processing and embedding
  • Sectioning and staining of paraffin-embedded and cryostat sections
  • Routine and special histological stains (see “Sample Submission” for the list of stains)
  • Immunohistochemistry (DAB or other labels including fluorescent labels) (see “Sample Submission” to select an antibody from BiCell Scientific catalog)
  • Immunofluorescence (Alexa Fluor 488 or other colors) (see “Sample Submission” to select an antibody from BiCell Scientific catalog)
  • In situ hybridization (DIG probes against mRNA or microRNA) (see “Sample Submission” to select a mRNA or microRNA probe)
  • Digital imaging using Nikon Ni-E motorized microscope

Each sample will have 2 consecutive sections on one slide with specified stain or label. Slides will be examined with light microscopy or epifluorescence microscopy. Slides with meaningful signals will be shipped to customers. Imaged micrographs will be sent to customers via BiCell Blue Cloud.

Turnaround time

  • Small orders of 10 samples or less – 5 days
  • Large orders of greater than 10 samples -2 weeks

Additional information

Service Type

Histologic stain on FFPE (per sample), Immunofluorescence on cryosection (per sample), Immunohistochemistry on FFPE (per sample), In situ hybridization on FFPE (per sample)

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"I am really impressed with your approach. We tried multiple times previously to create monoclonal and polyclonal antibodies to claudin-2 and MLCK1. We have had limited success generating polyclonals and no success generating monoclonals. You have generated outstanding monoclonals to both. I look forward to continuing to work with you."

Jerrold R. Turner, M.D., Ph.D.

Brigham and Women’s Hospital | Harvard Medical School

"The polyclonal antibody you generated for KIAA0408 is stunning! KIAA0408 is a novel cilium molecule that has never been studied. So, clearly there will be a lot of demand for it as we have discovered a very interesting finding and the story will be published in a high impact journal. I am strongly inclined to generate monoclonal antibody for this protein too and we should think about patenting it."

Univ.-Prof. Jay Gopalakrishnan PhD

Heinrich-Heine-Universität | Universitätsklinikum Düsseldorf

"Your ARL13B antibody works beautifully!!! We’re so happy to have a cilia-specific antibody made in rat! I can send you high resolution images to be posted on your website."

Julie Craft Van De Weghe, PhD

School of Medicine | University of Washington

"The assay is a homophilic interaction mediated cell adhesion on purified protein (in this case, immobilized purified Pcdhga9 to Pcdhga9 expressed on cell surface). Compared to control, cell adhesion is reduced in the presence of Pcdhga9 monoclonal antibody supernatants!"

Divyesh Joshi, PhD

School of Medicine | Yale University

"The rabbit hybridoma supernatants of anti-APOBEC3 project are tested positive by ELISA, and we are very happy about it! We previously tried a company, Abclone. Their Project "A" has immune response that is <10,000 titer in antiserum, which would explain why there is no positive mAb after fusion. Their project "B" didn't have any immune response in rabbit."

Harshita B Gupta, PhD.

School of Medicine | UT Health San Antonio

"We have tested anti mouse T cell antiserum samples from both rabbits you sent to us.

They worked very well! Thank you!"

Victoria Gorbacheva, PhD.

School of Medicine | Cleveland Clinic

Contact us for questions or custom requests!