Anti-IFT27 (BBS19) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Intraflagellar transport protein 27 homologue (IFT27), also known BBS19, is encoded by the IFT27 gene in human. IFT27 is the Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6.
IFT27 is found in the primary cilium. It is essential for male fertility, spermiogenesis and sperm flagella formation. Mutations in IFT27 cause Bardet-Biedl syndrome-19 (BBS19) (OMIM 615996), an autosomal recessive ciliopathy characterized by obesity, intellectual disability, polydactyly, renal failure, retinitis pigmentosa, and hypogonadism.
Reviews
There are no reviews yet.