Anti-JAM-A (F11R or CD321) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Junctional adhesion molecule A (JAM-A) is a protein that is encoded by the F11R gene in human. JAM-A is also known as CD321.
JAM proteins feature two extracellular immunoglobulin domains, a single transmembrane domain, and a cytoplasmic domain with a PDZ-binding motif. JAM-A can interact with ZO-1 via its PDZ-binding motif.
JAM-A is expressed in a variety of epithelial tissues.
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