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KCNB1 (Kv2.1) antibody labeling of mouse heart

KCNB1 (Kv2.1) antibody labeling of mouse heart

Kv2.1 proteins are localized to the sarcolemma of cardiac muscle fiber in the mouse heart.

High-magnification view of Kv2.1 in the mouse heart

High-magnification view of Kv2.1 proteins in the sarcolemma of myocardium of the mouse heart.

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KCNB1 (Kv2.1) antibody

$155.00 – $435.00

Item Cat No.: 20231

Antibody: Rabbit KCNB1 (Kv2.1) Polyclonal Antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, mouse, rat

Anti-KCNB1 (Kv2.1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

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Anti-KCNB1 (Kv2.1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

Potassium voltage-gated channel subfamily B member 1 (KCNB1), also known as Kv2.1, is Shab-related voltage-gated potassium channel that is encoded by the KCNB1 gene in human. Kv2.1 has 6 transmembrane domains labeled S1-S6, each with a tetrameric structure. Kv2.1 is a a delayed rectifier. Kv2.1 is expressed in pulmonary arteries, auditory outer hair cells, stem cells, the retina, and organs such as the heart and pancreas.

Host/Isotype: Rabbit/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (14-aa) derived from the C-terminal region of human Kv2.1 protein

Species homology of immunogen: Synthetic peptide sequence is identical to mouse or rat sequence

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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"I am really impressed with your approach. We tried multiple times previously to create monoclonal and polyclonal antibodies to claudin-2 and MLCK1. We have had limited success generating polyclonals and no success generating monoclonals. You have generated outstanding monoclonals to both. I look forward to continuing to work with you."

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Brigham and Women’s Hospital | Harvard Medical School

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Julie Craft Van De Weghe, PhD

School of Medicine | University of Washington

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