Anti-KCNJ2 (Kir2.1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Potassium inwardly rectifying channel subfamily J member 2 (KCNJ2), also known as Kir2.1, is an inward-rectifier type potassium channel that is encoded by the KCNJ2 gene in human. KCNJ2 participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in the KCNJ2 gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.
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