MTOR antibody

Anti-MTOR antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.

The mammalian target of rapamycin (mTOR), also referred to as the mechanistic target of rapamycin, and sometimes called FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a kinase that is encoded by the MTOR gene in human. This kinase is a component of two distinct complexes, mTORC1, which controls protein synthesis, cell growth and proliferation, and mTORC2, which is a regulator of the actin cytoskeleton, and promotes cell survival and cell cycle progression.

Mutations in this gene are associated with Smith-Kingsmore syndrome and somatic focal cortical dysplasia type II.