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NG2 (CSPG4) antibody labeling of mouse cerebrum

NG2 (CSPG4) antibody labeling of mouse cerebrum

NG2 proteins label oligodendrocyte progenitor cells in mouse cerebral cortex.

NG2 (CSPG4) antibody

$155.00 – $435.00

Item Cat No.: 02403

Antibody: Rat Anti-NG2 (CSPG4) polyclonal antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, Mouse, Rat

Anti-NG2 (CSPG4) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

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Anti-NG2 (CSPG4) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

Chondroitin sulfate proteoglycan 4 (CSPG4), also known as neuron-glial antigen 2 (NG2), is a chondroitin sulfate proteoglycan that is encoded by the CSPG4 gene in human. NG2 is a membrane protein, consisting in a large extracellular domain, a transmembrane domain and a cytoplasmic tail. NG2 is a marker protein of oligodendrocyte progenitor cells (OPCs) in the central nervous system.

Host/Isotype: Rat/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (14-aa) derived from the C-terminal region of human NG2 protein

Species homology of immunogen: Synthetic peptide sequence is identical to mouse or rat sequence

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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Julie Craft Van De Weghe, PhD

School of Medicine | University of Washington

"The assay is a homophilic interaction mediated cell adhesion on purified protein (in this case, immobilized purified Pcdhga9 to Pcdhga9 expressed on cell surface). Compared to control, cell adhesion is reduced in the presence of Pcdhga9 monoclonal antibody supernatants!"

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