NKCC1 (Slc12a2) (human) antibody

Anti-NKCC1 (Slc12a2) (human) antibody is recommended for immunofluorescence labeling, IHC, or western blot of materials from human tissues.

The Na-K-Cl cotransporter type 1 (NKCC1) protein is encoded by the SLC12A2 gene in human. NKCC1 consists in 12 transmembrane domains and the stoichiometry of the transported solutes is 1Na:1K:2Cl.

NKCC1 is highly expressed in organs that secrete fluids, such as exocrine glands and choroid plexus. In addition to exocrine glands, NKCC1 is important for establishing the potassium-rich endolymph that bathes the cochlea in the inner ear.

This antibody was raised against human specific epitope sequence in NKCC1 protein, which derives from a homologous region to the validated mouse NKCC1 epitope (Cat No.: 20302).