Anti-Occludin (Ocln) (N-terminus) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

Occludin belongs to a tight junction protein family of Marvel domain-containing proteins. The MARVEL [myelin and lymphocyte (MAL) and related proteins for vesicle trafficking and membrane link] domain is a tetraspan membrane structure that has originally been identified in proteins from the myelin and the lymphocytes.

Occludin is encoded by the Ocln gene in human. Occludin has four transmembrane domains, two extracellular loops (ECLs: ECL1 and ECL2), and amino- and carboxyl-terminal cytoplasmic domains.

Occludin is widely expressed by tissues of epithelial origin, which include the liver, the pancreas, the intestines, the lungs, the kidney, the blood vessel and more.

This antibody is raised in rat and against a different domain in Occludin compared to the antibody #00241.