Anti-Par3 (PARD3) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Partitioning defective 3 homolog (PARD3), also known as Par3, is encoded by the PARD3 gene in human. Par proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized cell growth.
Par3 is a membrane adapter protein containing multiple PDZ domains. Par3 is important for establishing not only apicobasal polarity, but also apical junctions.
Par3 is expressed by a variety of epithelial cell types.
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