PD-1 (PDCD1 or CD279) antibody

Anti-PD-1 (PDCD1 or CD279) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.

Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279), is a membrane protein that is encoded by the PDCD1 gene in human. PD-1 is a cell surface receptor that belongs to the immunoglobulin superfamily and is expressed on T cells and B cells. PD-1 is an immune checkpoint protein and guards against autoimmunity.

PD-1 antibodies, a new class of drugs that block PD-1, activate the immune system to attack tumors and are used to treat certain types of cancer.