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Antibody development strategy for human SGLT4 protein

3D predicted structure of SGLT4 protein is shown in the top panel. The bottom panel shows the alignment of extracellular domains of SGLT4 protein of human to mouse sequence (yellow highlight). Alphafold No: AF-Q2M3M2-F1.

SGLT4 (Slc5a9) (human) antibody

$155.00 – $435.00

Item Cat No.: 20809h

Antibody: Rat SGLT4 (Slc5a9) Polyclonal Antibody

Concentration: 0.25 mg/ml purified IgG

Application: Recommended for immunofluorescence labeling (1:100) and Western blot (1:1000)

Reactivity: Human

Anti-SGLT4 (Slc5a9) (human) antibody is recommended for immunofluorescence labeling, IHC, or western blot of materials from human tissues.

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Anti-SGLT4 (Slc5a9) (human) antibody is recommended for immunofluorescence labeling, IHC, or western blot of materials from human tissues.

Sodium-dependent glucose cotransporter 4, also known as sodium-glucose linked transporter 4 (SGLT4), is encoded by the SLC5A9 gene in human. Sglt4 is a new type of Na+-dependent glucose transporter, that transports mannose, 1,5-anhydro-D-glucitol, and fructose.

This antibody was raised against human specific epitope sequence in SGLT4 protein, which derives from a homologous region to the validated mouse SGLT4 epitope (Cat No.: 20809).

Host/Isotype: Rat/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (18-aa) derived from the N-terminal extracellular region of human Sglt4 protein

Species homology of immunogen: Synthetic peptide sequence showing 61.1% homology to mouse or rat sequence

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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"I am really impressed with your approach. We tried multiple times previously to create monoclonal and polyclonal antibodies to claudin-2 and MLCK1. We have had limited success generating polyclonals and no success generating monoclonals. You have generated outstanding monoclonals to both. I look forward to continuing to work with you."

Jerrold R. Turner, M.D., Ph.D.

Brigham and Women’s Hospital | Harvard Medical School

"The polyclonal antibody you generated for KIAA0408 is stunning! KIAA0408 is a novel cilium molecule that has never been studied. So, clearly there will be a lot of demand for it as we have discovered a very interesting finding and the story will be published in a high impact journal. I am strongly inclined to generate monoclonal antibody for this protein too and we should think about patenting it."

Univ.-Prof. Jay Gopalakrishnan PhD

Heinrich-Heine-Universität | Universitätsklinikum Düsseldorf

"Your ARL13B antibody works beautifully!!! We’re so happy to have a cilia-specific antibody made in rat! I can send you high resolution images to be posted on your website."

Julie Craft Van De Weghe, PhD

School of Medicine | University of Washington

"The assay is a homophilic interaction mediated cell adhesion on purified protein (in this case, immobilized purified Pcdhga9 to Pcdhga9 expressed on cell surface). Compared to control, cell adhesion is reduced in the presence of Pcdhga9 monoclonal antibody supernatants!"

Divyesh Joshi, PhD

School of Medicine | Yale University

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