Anti-Synemin (SYNM or Desmuslin) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Synemin, also known as desmuslin, is a protein that is encoded by the SYNM gene in human. Synemin is an intermediate filament (IF) family member. It localizes at the Z-disk and has been shown to bind to α-dystrobrevin, α-actinin, and desmin to act as a mechanical linker in transmitting force laterally throughout the tissue, especially between the contractile myofibrils and extracellular matrix.
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