Toll-like receptor 1 (TLR1 or CD281) antibody

Anti-Toll-like receptor 1 (TLR1 or CD281) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.

Toll-like receptor (TLR) family proteins play a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to human and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.

Toll-like receptor 1 (TLR1 or CD281) is a member of the TLR family that is encoded by the TLR1 gene in human. TLR1 recognizes bacterial peptidoglycan and (triacyl) lipopeptides by forming a heterodimer with TLR2.