Toll-like receptor 6 (TLR6 or CD286) antibody

Anti-Toll-like receptor 6 (TLR6 or CD286) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.

Toll-like receptor (TLR) family proteins play a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to human and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.

Toll-like receptor 6 (TLR6 or CD286) is a member of the TLR family that is encoded by the TLR6 gene in human. TLR6 forms a heterodimer with toll-like receptor 2 (TLR2). Its ligands include multiple diacyl-lipopeptides derived from gram-positive bacteria and mycoplasma and several fungal cell wall saccharides.