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Validated AGTR1 antibody


Item Cat No.: 50401

Antibody: Rabbit Polyclonal Antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, mouse, rat


Angiotensin-II receptors (type 1 and type 2) are a class of G protein-coupled receptors with angiotensin-II as their ligands. They play a role of signal transduction in the renin-angiotensin system to mediate the effect of vasoconstriction of angiotensin-II.

The type 1 of angiotensin-II receptor, also known as AT1 or AGTR1, is encoded by the AGTR1 gene in human. The AGTR1 protein contains seven transmembrane domains and multiple extracellular and intracellular domains.

AGTR1 is expressed by the heart, blood vessels, kidney, adrenal cortex, lung and brain to mediate the vasoconstriction effects.

Host/Isotype: Rabbit/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (14-aa) derived from the N-terminal extracellular region of human AGTR1 receptor protein

Species homology of immunogen: Synthetic peptide sequence is identical to mouse or rat sequence

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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