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Validated AGTR2 antibody


Item Cat No.: 50402

Antibody: Rabbit Polyclonal Antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Mouse, rat


Angiotensin-II receptors (type 1 and type 2) are a class of G protein-coupled receptors with angiotensin-II as their ligands. They play a role of signal transduction in the renin-angiotensin system to mediate the effect of vasoconstriction of angiotensin-II.

The type 2 of angiotensin-II receptor, also known as AT2 or AGTR2, is encoded by the AGTR2 gene in human. The AGTR2 protein contains seven transmembrane domains and multiple extracellular and intracellular domains.

AGTR2 is mainly expressed by fetal tissues and considered to play a neuronal role.

Host/Isotype: Rabbit/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (14-aa) derived from the N-terminal extracellular region of mouse AGTR2 receptor protein

Species homology of immunogen: Synthetic peptide sequence is identical to rat sequence (showing 50% homology to human sequence)

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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