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Validated Claudin-4 Antibody


Item Cat No.: 00204

Antibody: Rabbit polyclonal antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, Mouse, Rat


Claudin-4 is a protein that is encoded by the CLDN4 gene in human. Claudin-4 belongs to the Claudin protein superfamily.

Claudins are tetraspan proteins making the tight junction. Claudins have four transmembrane domains, two extracellular loops (ECLs: ECL1 and ECL2), amino- and carboxyl-terminal cytoplasmic domains, and a short cytoplasmic motif.

Claudin-4 is primarily expressed by the epithelium in the kidney, the lung, the pancreas and the intestines.

Host/Isotype: Rabbit/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (14-aa) derived from the C-terminal region of mouse Claudin-4 protein

Species homology of immunogen: Synthetic peptide sequence is identical to rat sequence (showing 85.7% homology to human sequence)

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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