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Validated DLG1 antibody


Item Cat No.: 00262

Antibody: Rabbit polyclonal antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, Mouse, Rat


Discs large homolog (DLG1), also known as synapse-associated protein 97 (SAP97), is encoded by the dlg1 gene in human. Mammalian DLG1 protein is homologous to Drosophila protein Dlg.

DLG1 is a cytosolic scaffold protein consisting of three PDZ domains, an SH3 domain, a I3 domain and a MAGUK domain. Drosophila Dlg1 protein plays a vital role in establishing the apicobasal polarity. Mammalian DLG1 protein is expected to perform a similar function. In addition, mammalian DLG family proteins have been shown to regulate adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation.

Host/Isotype: Rabbit/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (18-aa) derived from the C-terminal region of mouse DLG1 protein

Species homology of immunogen: Synthetic peptide sequence is identical to rat sequence (showing 94.4% homology to human sequence)

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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