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Validated NEPH2 antibody


Item Cat No.: 00178

Antibody: Rabbit Polyclonal Antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, mouse, rat


NEPH2, also known as Kin of IRRE-like protein 3 (KIRREL3), is encoded by the KIRREL3 gene in human. NEPH2 is a member of the NEPH protein family, which includes NEPH1 (KIRREL1) and NEPH3 (KIRREL2).

NEPH2 is found in the slit diaphragm of the kidney podocytes and can interact with Nephrin and CASK. NEPH2 consists of an extracellular N-terminal domain, a helical transmembrane domain, and a cytoplasmic C-terminal domain. NEPH2 has also been implicated in synapse formation. Genetic knockout of NEPH2 cause abnormal brain development.

Host/Isotype: Rabbit/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (18-aa) derived from the C-terminal region of human NEPH2 protein

Species homology of immunogen: Synthetic peptide sequence is identical to mouse or rat sequence

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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