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Validated Par6a antibody


Item Cat No.: 00249

Antibody: Rabbit polyclonal antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, Mouse, Rat


Partitioning defective 6 homolog alpha (PARD6A), also known as Par6a, is encoded by the PARD6A gene in human. Par proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized cell growth.

Par6a contains a PSD95/Discs-large/ZO1 (PDZ) domain and a Cdc42/Rac interactive binding (CRIB) domain.

Par6a is important for establishing the apicobasal polarity in developing epithelial tissues.

Host/Isotype: Rabbit/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (15-aa) derived from the C-terminal region of mouse Par6a protein

Species homology of immunogen: Synthetic peptide sequence is identical to rat sequence (showing 80% homology to human sequence)

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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