Anti-CCR1 (CD191) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.
Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. C-C chemokine receptor type 1 (CCR1) is a member of the beta chemokine receptor family, which is encoded by the CCR1 gene in human. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite.
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