Anti-CCR9 (CDw199) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.
Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. C-C chemokine receptor type 9 (CCR9) is a member of the beta chemokine receptor family, which is encoded by the CCR9 gene in human. CCR9 is highly expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine.
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