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NDCBE (Slc4a8) antibody


Item Cat No.: 20502

Antibody: Rabbit NDCBE (Slc4a8) Polyclonal Antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, mouse, rat


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Anti-NDCBE (Slc4a8) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

Electroneutral sodium bicarbonate exchanger 1, known as NDCBE, is encoded by the SLC4A8 gene in human. NDCBE mediates electroneutral sodium- and carbonate-dependent chloride-HCO3 exchange with a Na+:HCO3 stoichiometry of 2:1. NDCBE plays a major role in pH regulation in epithelium and neuron.

NDCBE consists in 11 transmembrane domains and is highly expressed by the epithelium in the kidney and the colon. NDCBE may interact with other chloride transporters such as CFTR or pendrin.

Host/Isotype: Rabbit/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (19-aa) derived from the C-terminal region of mouse NDCBE protein

Species homology of immunogen: Synthetic peptide sequence is identical to rat sequence (showing 84.2% homology to human sequence)

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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