Anti-CACNA1E (Cav2.3) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Calcium voltage-gated channel subunit alpha 1E, also known as Cav2.3, is a R-type voltage-dependent calcium channel that is encoded by the CACNA1E gene in human. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Cav2.3 is strongly expressed in the neural tissues such as cortex, hippocampus, striatum, amygdala and interpeduncular nucleus.
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