Anti-CCR8 (CDw198) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.
Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. C-C chemokine receptor type 8 (CCR8) is a member of the beta chemokine receptor family, which is encoded by the CCR8 gene in human. CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis.
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