Shop Antibodies

Claudin-2 (CLDN2) monoclonal antibody (E5 clone)

$175.00$545.00

Item Cat No.: 00202e5

Antibody: Mouse Anti-Claudin-2 (CLDN2) monoclonal antibody

Concentration: Purified IgG - 0.25 mg/ml

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, Mouse, Rat

Anti-Claudin-2 (CLDN2) monoclonal antibody (E5 clone) is validated on mouse and human tissues and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. The E5 clone is particularly suited for IHC applications on FFPE sections.

Optional Blocking Peptide

Product price
Additional options total:
Order total:

Anti-Claudin-2 (CLDN2) monoclonal antibody (E5 clone) is validated on mouse and human tissues and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. The E5 clone is particularly suited for IHC applications on FFPE sections.

Claudin-2 is a protein that is encoded by the CLDN2 gene in human. Claudin-2 belongs to the Claudin protein superfamily.

Claudins are tetraspan proteins making the tight junction. Claudins have four transmembrane domains, two extracellular loops (ECLs: ECL1 and ECL2), amino- and carboxyl-terminal cytoplasmic domains, and a short cytoplasmic motif.

Claudin-2 is primarily expressed in intestinal crypts and is strongly upregulated in inflammatory diseases of the intestines.

Host/Isotype: Mouse/IgG

Class: Monoclonal

Immunogen: Synthetic peptide (13-aa) derived from the C-terminal region of human Claudin-2 protein

Species homology of immunogen: Synthetic peptide sequence is identical to mouse or rat sequence

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C


For Research Use Only. Not for use in clinical diagnostics.

Reviews

There are no reviews yet.

Be the first to review “Claudin-2 (CLDN2) monoclonal antibody (E5 clone)”

"I am really impressed with your approach. We tried multiple times previously to create monoclonal and polyclonal antibodies to claudin-2 and MLCK1. We have had limited success generating polyclonals and no success generating monoclonals. You have generated outstanding monoclonals to both. I look forward to continuing to work with you."

Jerrold R. Turner, M.D., Ph.D.

Brigham and Women’s Hospital | Harvard Medical School

"The polyclonal antibody you generated for KIAA0408 is stunning! KIAA0408 is a novel cilium molecule that has never been studied. So, clearly there will be a lot of demand for it as we have discovered a very interesting finding and the story will be published in a high impact journal. I am strongly inclined to generate monoclonal antibody for this protein too and we should think about patenting it."

Univ.-Prof. Jay Gopalakrishnan PhD

Heinrich-Heine-Universität | Universitätsklinikum Düsseldorf

"Your ARL13B antibody works beautifully!!! We’re so happy to have a cilia-specific antibody made in rat! I can send you high resolution images to be posted on your website."

Julie Craft Van De Weghe, PhD

School of Medicine | University of Washington

"The assay is a homophilic interaction mediated cell adhesion on purified protein (in this case, immobilized purified Pcdhga9 to Pcdhga9 expressed on cell surface). Compared to control, cell adhesion is reduced in the presence of Pcdhga9 monoclonal antibody supernatants!"

Divyesh Joshi, PhD

School of Medicine | Yale University

Contact us for questions or custom requests!