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IMMT (Mitofilin or Mic60) antibody labeling of mouse kidney

IMMT (Mitofilin or Mic60) antibody labeling of mouse kidney

IMMT proteins are found in the inner mitochondrial membrane of the epithelium in the inner medulla of the mouse kidney.

IMMT in embryonic mouse lung

IMMT proteins are found expressed by the alveolar epithelium as well as the bronchial epithelium (B) in the lung from a mouse embryo at E15.5.

IMMT in embryonic mouse somite

IMMT proteins are found expressed by the progenitor cells in the somite from a mouse embryo at E15.5.

IMMT (Mitofilin or Mic60) antibody

$155.00 – $435.00

Item Cat No.: 54210

Antibody: Rat IMMT (Mitofilin or Mic60) Polyclonal Antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, mouse, rat

Anti-IMMT (Mitofilin or Mic60) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

Optional Blocking Peptide

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Anti-IMMT (Mitofilin or Mic60) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

Inner membrane mitochondrial protein (IMMT), also known as Mitofilin or Mic60, is encoded by the IMMT gene in human. IMMT is a core subunit of the MICOS-complex, directly located next to cristae junctions (CJ). IMMT is anchored to the inner mitochondrial membrane via its N-terminus, while most of the C-terminus of the protein is located to the inner mitochondrial space.

Host/Isotype: Rat/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (16-aa) derived from the C-terminal mitochondrial intermembrane region of mouse IMMT protein

Species homology of immunogen: Synthetic peptide sequence is identical to rat sequence (showing 93.8% homology to human sequence)

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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"I am really impressed with your approach. We tried multiple times previously to create monoclonal and polyclonal antibodies to claudin-2 and MLCK1. We have had limited success generating polyclonals and no success generating monoclonals. You have generated outstanding monoclonals to both. I look forward to continuing to work with you."

Jerrold R. Turner, M.D., Ph.D.

Brigham and Women’s Hospital | Harvard Medical School

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Julie Craft Van De Weghe, PhD

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