Anti-NPT2a (SLC34a1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Sodium-dependent phosphate transport protein 2A (NPTIIa or NPT2a), also known as Na+-Pi-cotransporter 2a (NaPi-2a), or SLC34a1, is encoded by the SLC34A1 gene in human.
NPTIIa consists in 8 transmembrane domains and is highly expressed in the proximal tubules of the kidney, where its function is tightly regulated by the PTH hormone.
Mutations in NPTIIa cause hypophosphatemia with nephrolithiasis and osteoporosis.
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