Anti-ORAI1 (TAM2 or TMEM142A) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Calcium release-activated calcium channel protein 1 is a calcium selective ion channel that is encoded by the ORAI1 gene in human. ORAI1 is activated by the calcium sensor STIM1 when calcium stores are depleted. Mutations in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).
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