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SCN2A (Nav1.2) antibody


Item Cat No.: 20352

Antibody: Rabbit SCN2A (Nav1.2) Polyclonal Antibody

Concentration: 0.25 mg/ml purified IgG

Application: Validated by immunofluorescence labeling (1:100)

Reactivity: Human, mouse, rat


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Anti-SCN2A (Nav1.2) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.

Nav1.2, also known as sodium voltage-gated channel alpha subunit 2 (SCN2A), is a protein that is encoded by the SCN2A gene in human. Nav channels function in the generation and propagation of action potentials in neurons. Each Nav channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits. Allelic variants of the SCN2A gene are associated with seizure disorders and autism spectrum disorder.

Host/Isotype: Rabbit/IgG

Class: Polyclonal

Immunogen: Synthetic peptide (14-aa) derived from the C-terminal region of human Nav1.2 protein

Species homology of immunogen: Synthetic peptide sequence is identical to mouse or rat sequence

Conjugation: Unconjugated

Purification: Affinity chromatography

Storage buffer: PBS, pH 7.2, 0.1% sodium azide

Storage condition: –20°C

For Research Use Only. Not for use in clinical diagnostics.

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