Anti-Tau (MAPT) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Microtubule associated protein Tau (MAPT) is encoded by the MAPT gene in human. Tau plays a role in maintaining the stability of microtubules in axons. The accumulation of hyperphosphorylated tau in neurons is associated with neurofibrillary degeneration. Mutations in MAPT gene have been associated with several neurodegenerative disorders such as Alzheimer’s disease, Pick’s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
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