Anti-BBS3 (ARL6) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
ADP-ribosylation factor-like protein 6 (ARL6), also known as BBS3, is encoded by the ARL6 gene in human. The ARL6 protein belongs to the ARF-like (ADP ribosylation factor-like) sub-family of the ARF family of GTP-binding proteins which are involved in regulation of intracellular trafficking.
Mutations in BBS3 cause Bardet–Biedl syndrome, an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation, and mental retardation (OMIM 600151).
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