Anti-CCR7 (CD197) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.
Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. C-C chemokine receptor type 7 (CCR7) is a member of the G protein-coupled receptor family, which is encoded by the CCR7 gene in human. CCR7 is expressed by various cancer cells, such as nonsmall lung cancer, gastric cancer and oesophageal cancer.
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