Anti-CDKN1B (P27 or P27KIP1 or KIP1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues.
Cyclin-dependent kinase inhibitor 1B (p27Kip1) is an enzyme inhibitor that is encoded by the CDKN1B gene in human. CDKN1B belongs to the Cip/Kip family of cyclin dependent kinase (Cdk) inhibitor proteins. CDKN1B binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1.
Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).
Reviews
There are no reviews yet.