Anti-WNK1 antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
WNK lysine deficient protein kinase 1 or WNK1 is an enzyme that is encoded by the WNK1 gene in human.
WNK1 is highly expressed in the kidney tubules where it interacts with WNK4. WNK1 plays a vital role in the regulation of extracellular fluid volume and blood pressure.
Mutations in WNK1 cause a dominant form of pseudohypoaldosteronism type 2 (PHA-II), also known as Gordon syndrome (OMIM 614492).
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