Anti-DLG2 (PSD-93 or chapsyn-110) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Discs large homolog (DLG2), also known as postsynaptic density protein 93 (PSD-93) or channel-associated protein of synapse-110 (chapsyn-110), is encoded by the dlg2 gene in human.
DLG2 is a cytosolic scaffold protein consisting in three PDZ domains, an SH3 domain, and a guanylate kinase-like domain. Drosophila Dlg protein plays a vital role in establishing the apicobasal polarity. Mammalian DLG family proteins play more roles that include adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation.
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