Anti-CLPP (PRLTS3 or DFNB81) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
ATP-dependent Clp protease proteolytic subunit (ClpP) is an enzyme that is encoded by the CLPP gene in human. This protein is an essential component of the protein complex of endopeptidase Clp. ClpP protease is a major contributor for mitochondrial protein quality control system and removing damaged or misfolded proteins in mitochondrial matrix. Defects in mitochondrial Clp proteases have been associated with the progression of neurodegenerative diseases.
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