Anti-Connexin-37 (Cx37 or Gja4) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues.
Connexins are the structural proteins making the gap junction. Each gap junction is composed of two hemichannels, or connexons, which consist of a hexameric assembly of connexin proteins.
Connexin-37 is encoded by the Gja4 gene in human. Connexin-37 is also known as gap junction protein alpha-4. Connexins have four transmembrane domains, two extracellular loops, amino- and carboxyl-terminal cytoplasmic domains, and a cytoplasmic turn motif.
Connexin-37 is highly expressed in the ovary and the heart.
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